WebSep 21, 2024 · It has been reported that the levels of TGF-β 1 on patients with null-mild liver fibrosis are higher than those with advanced liver fibrosis, which hint that TGF-β 1 may … WebJan 13, 2024 · Connective tissue growth factor (CTGF) is involved in the regulation of extracellular matrix (ECM) production. Elevated levels of CTGF can be found in plasma from patients with liver fibrosis and in experimental animal models of liver fibrosis, but the exact role of CTGF in, e.g., diet-induced human liver fibrosis is not entirely known. To …
Selective deletion of hepatocyte platelet-derived growth factor ...
WebAug 28, 2024 · A similar effect of sol-Eng on secreted CTGF in the supernatant is seen at higher ligand concentrations. ... the noncoding RNA-H19 enhance transdifferentiation of cultured mouse primary HSC and promote progression of cholestatic liver fibrosis . … WebMar 20, 2024 · Liver fibrosis (LF) is caused by chronic liver injury from various causes, such as viral infections, alcohol consumption, non-alcoholic fatty liver disease (NAFLD), … easy asian dessert ideas
Exosomes in liver fibrosis: The role of modulating hepatic stellate ...
WebSep 1, 2006 · Results: The mean concentration of CTGF was highest in the fibrosis group (5.2-fold) and in the chronic viral hepatitis group (4.3-fold) but lower in those patients with fully developed cirrhosis. The area under the ROC curve (AUC) of CTGF for fibrosis vs control was 0.955 (95% confidence interval, 0.890–0.987). WebSep 16, 2012 · CTGF is overexpressed in human liver fibrosis/cirrhosis of various aetiologies and in experimental liver fibrogenesis [ 12 - 16 ]. It is a major fibrogenic signal, with TGF-β-dependent activity when produced in hepatocytes, and TGF-β-independent activity when derived from HSCs [ 17 ]. WebApr 11, 2024 · various inflammatory modulators, including TGF-β and CTGF, in a paracrine manner has been reported. In addition to ... Liver fibrosis is a common pathological process of chronic liver diseases ... easy asian food to cook