Web7 Q5.In the box below, you are given the pKa values for a series of compounds, the least acidic is cyclohexanol (pKa = 16.0). The pKa value for phenol is 10.0, and two series of substituted phenols are given: 2-fluorophenol, 3-fluorophenol, and 4-fluorophenol have pKa values of 8.7, 9.3, and 9.9, respectively; 2-nitrophenol, 3-nitrophenol, and 4 … WebAug 27, 2024 · The $\mathrm{p}K_\mathrm{a}$ value of o-fluorophenol is $8.7$, while that of the p-fluorophenol is $9.9$. It's obvious that the inductive effect is more dominant at ortho-position, which results in a more acidic nature.
3-Chloro-4-fluorophenol 98 2613-23-2
WebSince fluorine and chlorine are both − I groups, the acidic strength of 3-fluorophenol should be higher but due to its contribution to resonance ( + R effect) in the aromatic ring, 3-fluorophenol becomes less acidic. Share Improve this answer Follow edited Jul 3, 2024 at 14:31 orthocresol 69.6k 11 232 393 answered Jul 3, 2024 at 14:10 Mitchell WebFluorenol, also known as hydrafinil, is an alcohol derivative of fluorene.In the most significant isomer, fluoren-9-ol or 9-hydroxyfluorene, the hydroxy group is located on the bridging … esp prosthetic valve
4-Fluorophenol C6H5FO - PubChem
WebJan 1, 1996 · 4-Fluorophenol is widely used intermediate in the industrial production of pharmaceuticals cisapride and Sabeluzole from Janssen, Sorbinil from Pfizer, Progabide from Synthelabo and more recently agrochemical specialities. Web3-Fluorophenol. Molecular Formula CHFO. Average mass 112.102 Da. Monoisotopic mass 112.032440 Da. ChemSpider ID 9360. Web2-fluorophenol (ortho), 3-fluorophenol (meta), and 4-fluorophenol (para) have pKa values of 8.7, 9.3, and 9.9, respectively. More the pKa value lesser the acidity. So 2-fluorophenol i.e. o-fluorophenol is more acidic because proximity. That is orthofluoro phenoxide ion will be stabilized by electron withdrawing effect of F atom present nearby. finn the shark